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Acotiamide monohydrochloride trihydrate

🥰Excellent
Catalog No. T2319Cas No. 773092-05-0
Alias Z-338 HCl, YM-443 HCl, Acotiamide hydrochloride

Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.

Acotiamide monohydrochloride trihydrate

Acotiamide monohydrochloride trihydrate

🥰Excellent
Purity: 99.48%
Catalog No. T2319Alias Z-338 HCl, YM-443 HCl, Acotiamide hydrochlorideCas No. 773092-05-0
Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.
Pack SizePriceAvailabilityQuantity
200 mg$35In Stock
500 mg$55In Stock
1 g$78In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.48%
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Product Introduction

Bioactivity
Description
Acotiamide monohydrochloride trihydrate (Z-338 HCl) is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.
AliasZ-338 HCl, YM-443 HCl, Acotiamide hydrochloride
Chemical Properties
Molecular Weight541.06
FormulaC21H37ClN4O8S
Cas No.773092-05-0
Smiless1c(nc(c1)C(=O)NCCN(C(C)C)C(C)C)NC(=O)c1c(cc(c(c1)OC)OC)O.O.Cl.O.O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/mL (50.83 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8482 mL9.2411 mL18.4822 mL92.4112 mL
5 mM0.3696 mL1.8482 mL3.6964 mL18.4822 mL
10 mM0.1848 mL0.9241 mL1.8482 mL9.2411 mL
20 mM0.0924 mL0.4621 mL0.9241 mL4.6206 mL
50 mM0.0370 mL0.1848 mL0.3696 mL1.8482 mL

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